donor rejection before living donor liver transplantation: causes and cost effective analysis in an egyptian transplant center.
نویسندگان
چکیده
background in the living donor liver transplant setting, the preoperative assessment of potential donors is important to ensure the donor safety. objectives the aim of this study was to identify causes and costs of living liver-donors rejection in the donation process. materials and methods from june 2010 to june 2012, all potential living liver donors for 66 liver transplant candidates were screened at the ain shams center for organ transplantation. potential donors were evaluated in 3 phases, and their data were reviewed to determine the causes and at which phase the donors were rejected. results one hundred and ninety two potential living liver donors, including 157 (81.7%) males, were screened for 66 potential recipients. of these, 126 (65.6%) were disqualified for the donation. the causes of rejection were classified as surgical (9.5 %) or medical (90.5 %). five donors (3.9 %) were rejected due to multiple causes. factor v leiden mutation was detected in 29 (23 %) rejected donors (p = 0.001), 25 (19.8 %) donors had positive results for hepatitis serology (p = 0.005), and 16 (12.7 %) tested positive for drug abuse. portal vein trifurcation (n = 9, 7.1%) and small size liver graft estimated by ct volumetric analysis (n = 6, 4.8 %) were the main surgical causes which precluded the donation. conclusions among potential egyptian living liver donors, factor v leiden mutation was a significant cause for live donor rejection. a stepwise approach to donor assessment was found to be cost-effective.
منابع مشابه
Donor Rejection Before Living Donor Liver Transplantation: Causes and Cost Effective Analysis in an Egyptian Transplant Center.
BACKGROUND In the living donor liver transplant setting, the preoperative assessment of potential donors is important to ensure the donor safety. OBJECTIVES The aim of this study was to identify causes and costs of living liver-donors rejection in the donation process. MATERIALS AND METHODS From June 2010 to June 2012, all potential living liver donors for 66 liver transplant candidates wer...
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[30] Nakamura T, Tanaka K, Kiuchi T, Kasahara M, Oike F, Ueda M, et al. Anatomical variations and surgical strategies in right lobe living donor liver transplantation: lessons from 120 cases. Transplantation 2002;73:1896–1903. [31] Egawa H, Oike F, Buhler L, Shapiro AM, Minamiguchi S, Haga H, et al. Impact of recipient age on outcome of ABO-incompatible livingdonor liver transplantation. Transp...
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OBJECTIVES The introduction of the living donor liver transplantation (LDLT) in Egypt as in elsewhere, has raised important psychological conflicts and ethical questions. The objective of this study was to get better understanding of the potential donors' motives toward LDLT. METHODS This study was conducted on consecutive 193 living-liver donors who underwent partial hepatectomy as donors fo...
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عنوان ژورنال:
hepatitis monthlyجلد ۱۴، شماره ۱، صفحات ۰-۰
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